Where the 49ers Will be Challenged the Most Against the Texans

Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a typical 2-4 losing team. They boast o

Texans vs. 49ers prediction, pick, odds for Sunday's NFL Week 8 game - 10/26/2025

Get a prediction, pick and odds for the NFL Week 8 matchup between the Houston Texans and the San Francisco 49ers.

ESPN insider connects 49ers to possible trade for Texans LB playing under DeMeco Ryans

The San Francisco 49ers need a linebacker and it just so happens their old friend, Houston Texans head coach DeMeco Ryans, likely has one available for trade ahead of the deadline.

Texans Rule Two Key Players Out vs. 49ers

According to NFL Network insider Tom Pelissero, the Texans are ruling out wide receiver Nico Collins, who suffered a concussion in Week 7 against the Seattle Seahawks, and Christian Kirk, who hasn't played since Week 5 with a hamstring injury.

Can 49ers’ patchwork defense match up with Texans’ top unit?

The 49ers (5-2) will take on the NFL’s stingiest scoring defense Sunday in Houston while Robert Saleh must patch up another hole in the Niners’ defense.
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