The San Francisco 49ers, led by quarterback Brock Purdy, face the Cleveland Browns, led by quarterback Shedeur Sanders, on Sunday, Nov. 30, 2025 at Huntington Bank Field in Cleveland, Ohio.

Catch the 49ers take on the Panthers on Monday, November 24. Here's everything you need to know about how to stream the game.

The San Francisco 49ers are back at Levi’s Stadium in Week 12 of the NFL season with a “Monday Night Football” matchup set against the Carolina Panthers.

The San Francisco 49ers won their first game in Cleveland since November 11, 1984. Kyle Shanahan and his offense defeated Jim Schwartz’s defense. Brock Purdy played well in a cold-weather game. The narratives fell one by one with a 26-8 victory over Shedeur Sanders and the Browns.

Depth has been severely lacking on the San Francisco 49ers this season. That’s because every time anyone looks up, a player is getting injured. That was the cas

Preview the San Francisco 49ers' NFL Week 13 matchup with the Browns and find out who is on the injury report.

Get the best Panthers vs. 49ers predictions and odds ahead of their Monday Night Football clash at Levi's Stadium. Free NFL picks for November 24.

The best-case scenario for everybody involved might be Bethune plays on early downs, and Kendrick comes in during obvious passing downs or sub-packages. You’re never going to replace Fred Warner fully, but that duo is as close as the 49ers can get.