Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

For decades, Americans have been told a simple story about addiction: taking drugs damages the brain—and the earlier in life children start using substances, the more likely they are to progress ...

For weeks, Steele, an assistant professor of psychiatry at the Yale School of Medicine, and members of his lab have traveled to an addiction treatment center in Middletown, Connecticut, where they are ...

Researchers combined 11 international resting-state fMRI datasets to map how psychedelic drugs reshape brain connectivity ...

Your heart pounds, thoughts obsess over one person, and rational thinking flies out the window. Love doesn’t just feel like a drug – your brain literally processes it like one. Understanding this ...

(THE CONVERSATION) Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse ...

Evidence is mounting that the wildly popular weight-loss medicines known as GLP-1s may also hold potential for treating addiction, and the field may be on the verge of obtaining desperately needed ...

Last April, neuroscientist Sue Grigson received an e-mail from a man detailing his years-long struggle to kick addiction — first to opioids, and then to the very medication meant to help him quit. The ...

I WANT TO eat. I need to eat. I shouldn’t eat. I just ate. Why do I want to eat more? Oh my god: Why am I constantly thinking about this? This is so ridiculous. I hate this. I’m ashamed of this. This ...

The complexities of addiction have stumped scientists for decades. Today, with 48 million Americans over the age of 12 suffering from a substance use disorder, and alcohol and drugs combined resulting ...