Parasites that cause the deadly illness known as sleeping sickness can spread beyond their native Africa as a result of mutations to key genes, a study shows. A parasite which has devastating impacts ...

To escape the grip of the human immune system, Trypanosoma brucei, which causes African sleeping sickness, performs its acclaimed disappearing act. Every time the host's immune cells get close to ...

While scientists have known for years that African trypanosomes cause sleeping sickness, they've been left scratching their heads as to how these tiny single-celled organisms communicate. A University ...

The African trypanosome, a blood parasite that causes African sleeping sickness, is like a fugitive that changes its "coat" each time the human immune system is about to nab it. Woven of 10 million ...

African trypanosomes establish deadly, chronic infections of trypanosomiasis in the bloodstream by using repetitive 70-bp regions in the genome to regularly change out the active coat protein gene.

This video shows nanotubes giving rise to small extracellular vesicles. University of Georgia researchers discovered that long filaments -- that look like beads on a string -- form by budding from the ...

Trypanosomatids are parasites that can result in more than 1 billion potentially fatal infections per year globally. In Africa, Human African Trypanosomiasis (HAT), better known as sleeping sickness, ...

African trypanosomes cause disease in man and domestic animals. The parasites have the ability to escape immune control by two means: by antigenic variation of the surface glycoprotein coat so that ...

We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of Trypanosoma brucei rhodesiense infection were genetically distinct as ...

The rate and conformational orientation of positive charges and hydrophobic residues in the molecule seem to be structural requirements for their trypanolytic activity. Thus, although the VIP fragment ...