Among patients with incident rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) who were new antimalarial users, adherence to antimalarials (≥ 90% of doses) was associated with a lower ...

Opportunities center on resistance-ready combination therapies and pediatric, pregnancy-compatible, heat-stable formulations across antimalarial, anthelmintic, and antiprotozoal segments. Africa and ...

Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization. In each drug, a carefully concocted formula of natural and synthetic enzymes and ...

After screening a library of over 100,000 small molecules, researchers from the Broad Institute of MIT and Harvard have identified compounds that act on a novel target in the malaria parasite, ...

The battle to control malaria infection has been hampered by many factors, including emerging drug resistance. Now, two papers published in Nature have opened up the door to a wealth of compounds that ...

Artemisinin-based combination treatments (ACTs) are seen as an important tool in the global effort to roll back malaria. With parasite resistance to chloroquine increasing rapidly in many parts of the ...

Researchers have developed novel ferrocene-based molecules that impair the malaria parasite's metabolic function leading to parasite death. A team of researchers from the Singapore University of ...

New research published today in Antimicrobial Agents and Chemotherapy, shows that the well-established group of antimalarials, known as artemisinins, are unlikely to be affected by resistance. The ...

Malaria medicines that are too weak or downright fakes are harming health and could aggravate drug resistance, says epidemiologist Paul Newton It’s big. A recent review by the WorldWide Antimalarial ...

Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization. In each drug, a carefully concocted formula of natural and synthetic enzymes and ...