Medscape

APAF-CRT: 'Ablate and Pace' Cuts Mortality in Narrow-QRS HF, Permanent AF

In the APAF-CRT trial, mortality fell more than 70% over 4 years for such patients with HF and narrow QRS intervals who were assigned to ablate-and-pace — that is, CRT after creation of heart block by ...
Medscape

APAF-CRT: 'Ablate and Pace' for Permanent AF With Heart Failure, Narrow QRS

MUNICH — Patients with heart failure (HF) and narrow electrocardiographic QRS intervals aren't considered appropriate for cardiac resynchronization therapy (CRT), but evidence is growing that CRT may ...
Nature

Variants in Apaf-1 segregating with major depression promote apoptosome function

It was necessary to amplify the gene in two pieces (using primers A1+A2, and A3+A4), which were subsequently ligated using the internal EcoRI site at base 2630 in NM_181861. The resultant APAF1 was ...
TCTMD

AV Junction Ablation Plus CRT Cuts Deaths in Permanent AF Subset

Atrioventricular (AV) junction ablation plus cardiac resynchronization therapy (CRT) reduces mortality in patients with symptomatic permanent atrial fibrillation (AF), a narrow QRS, and a recent heart ...
ascopubs.org

Loss of Apaf-1 expression and resistance to hypoxia-induced apoptosis in cervical cancer

Serum YKL-40 levels in patients with cervical cancer are elevated compared to patients with cervical intraepithelial neoplasia and healthy controls No significant financial relationships to disclose.
MedPage Today

Ablation, CRT Boost Survival in Permanent Afib With Narrow QRS

A "pace-and-ablate" strategy substantially boosted survival for permanent atrial fibrillation (Afib) patients with a narrow QRS across the range of left ventricular ejection fraction (LVEF), the ...