Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Ferroptosis is a distinct form of regulated cell death that is iron-dependent and characterized by excessive lipid peroxidation. It has emerged as a critical mechanism implicated in the ...

Multiple sclerosis, which affects around one in 500 people in Switzerland, is an autoimmune disease in which immune cells ...

Neurodegenerative disorders, such as Alzheimer's, Parkinson's, and Huntington's diseases, are characterized by progressive ...

Cancer thrives by hijacking the body's own basic survival systems, making it hard to attack tumors without collateral damage ...

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Scientists have found a new way to stop cancer growth without damaging healthy cells. Researchers from the Francis Crick Institute and Vividion Therapeutics discovered a compound that blocks the ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...