The Niners played an instant classic between two great quarterbacks Sunday night, but it was San Francisco that got the last laugh in its 42-38 victory over the Chicago Bears.

Brock Purdy threw for 303 yards and three touchdowns as San Francisco is now one win away from earning the NFC's top seed.

The 49ers (11-4) will miss their play-making tight end while at the same time welcome back one of their top receivers when ...

The 49ers came away with an exhilarating 42-38 win over the Bears on Sunday night. While Chicago's defense came to play on the first snap, when T.J. Edwards returned a Brock Purdy interception for a ...

Coach Kyle Shanahan has the 49ers in prime position with two games remaining in the regular season. It is simple. If the 49ers win their final two games in the regular season, they will be the No. 1 ...

Even after George Kittle was lost to a torn Achilles tendon, San Francisco knocked off the defending Super Bowl champion ...

The Seahawks claimed the No. 1 seed in the NFC after defeating the 49ers in Week 18. USA TODAY Sports provided updates, ...