These burrowing animals have a biological mechanism that does the opposite of what it does in humans: it repairs DNA instead ...

A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...

Blocking meiotic DNA replication in budding yeast prevents recombination initiation. This could indicate a direct coupling of the two processes, or the presence of a checkpoint system that detects ...

BRCA gene expression is induced at the G1/S boundary in cultured cell lines (Gudas et al., 1996; Vaughn et al., 1996a,b) and primary tissues (Blackshear et al., 1998; Rajan et al., 1996), and the ...

The INO80 chromatin remodelling complex has various roles in genome maintenance, acting via nucleosome sliding and H2A.Z ...

What naked mole-rats lack in the looks department they make up for it in longevity, living healthily for nearly four decades.

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...

Researchers in China have determined to identify the genetic basis for the naked mole-rats’ increased longevity.

The secret to the naked mole-rats’ extraordinarily long life may lie in subtle changes to just four amino acids, researchers report. According to a new study, evolutionary mutations in cGAS – an ...

Distinguishing Renal Cell Carcinoma From Normal Kidney Tissue Using Mass Spectrometry Imaging Combined With Machine Learning Homologous recombination DNA repair deficiency (HRD) is a therapeutic ...

Lymphocyte Infiltration Score and Spatial Characteristics Refined the Prognosis and Denosumab Treatment Responsiveness Indicators for Giant Cell Tumor of Bone Outcomes data for DNA-damaging ...