Weight-loss responses to GLP-1 obesity drugs, and risks of side effects, may be linked to genetic variants, according to a ...

Using base editing, researchers targeted a genetic mutation linked to severe epilepsy. The approach reduced seizures and ...

A genetic fault long believed to drive the development of esophageal cancer may in fact play a protective role early in the disease, according to new research published in Nature Cancer. This ...

In a new study published in Nature Genetics titled, “The long-term effects of chemotherapy on normal blood cells,” researchers from the Wellcome Sanger Institute, the University of Cambridge, and ...

Sitting in my doctor's examination room, I was surprised when she told me, "Genetics don't really matter for chronic disease." Rather, she continued, "A person's lifestyle, what they eat, and how much ...

Investigators have unveiled for the first time that changes in certain genes affect an aggressive cancer, T-cell acute lymphoblastic leukemia (T-ALL), differently depending on genetic ancestry. The ...

In the mountains of northwestern Colombia, thousands of members of extended families carry a single genetic mutation that all but guarantees they will develop Alzheimer’s disease before age 50. For ...

University of Virginia School of Medicine scientists have used a next-generation form of gene editing to fix the underlying cause of a severe form of epilepsy in lab mice.

Tobacco smoking is linked to specific genetic mutations in MDS, affecting chromatin modification and RNA splicing pathways. A dose-response relationship exists, with higher smoking intensity ...

In humans, hundreds of proteins interact in a complex network dubbed the interactome. Those interactions are further complicated when disease-causing mutations are introduced into genes that code for ...