The lipopolysaccharides, or endotoxins, are made up of O-antigens, a core polysaccharide, and lipid A, which is made up of glucosamine and fatty acids and is responsible for the toxic effects. The ...

Escherichia coli is widely considered the most cost-effective bacterial system for recombinant protein expression. Consequently, it is broadly used. Nonetheless, it has its limitations as an ...

CHICAGO -- Blood purification using polymyxin B showed a mortality reduction signal in patients with septic shock and high endotoxin activity, researchers reported here. In the phase III Tigris trial, ...

Thermo Fisher Scientific has introduced the Thermo Scientific Pierce High Capacity Endotoxin Removal Resin for the cleanup of protein that is injected or transfected into cells or animals. The Pierce® ...

Preparing sterile products requires manufacturers to control microbial quality. Sterility and endotoxin content are critical because failure to properly manage them can seriously harm, or even kill, ...

Tissue and cell culture are important tools in numerous fields of biomedical research. Most steps of the tissue culture process make use of water, including media and buffer preparation and glassware ...