FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...
Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...
Sepsis, a life-threatening condition caused by dysregulated host response to infection, remains a major cause of global ...
For decades, Parkinson’s disease research focused almost exclusively on protein misfolding, but 2025-2026 lipidomics breakthroughs have upended this view by demonstrating that lipid droplets actively ...
Transcriptomic phenotyping offers mechanistic insight into adipocyte biology and metabolic disease. A signature of adipocyte ...
To investigate the role of KIF13B in SICD, a research team led by Prof. Xunde Xian from Peking University conducted a series ...
Intermittent fasting is associated with extending lifespan. However, a recent study from UT Southwestern challenges this idea ...