LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.

Lipids are fatty molecules that play critical roles in cell function, including membrane structure, energy storage and nutrient absorption. Most lipids are made in a cell organelle called the ...

When we consume fats (also called lipids) in our diet, they can be metabolized or stored to provide energy for the body. But they are also involved in regulating the genes expressed within—and the ...

Obesity and obesity-associated diseases, such as type 2 diabetes mellitus and cardiovascular diseases, have reached pandemic levels worldwide and are major threats to human life. Lipid species within ...

OHSU scientists Fikadu Tafesse, Ph.D., at left, and Carsten Schultz, Ph.D., are leading the development of a new database and dashboard available to the world’s scientists to better understand how ...

A team from Geneva, Switzerland, shows that the disruption of lipid temporal profiles in type 2 diabetes stiffens the membrane of pancreatic endocrine cells, which could alter their function. Like all ...

Scientists who add detergents to their cell preps, take heed: You might be consigning the most interesting stuff to the trash bin. Not proteins, surely, or nucleic acids, but lipids. A class of ...

Precise quantification and annotation of individual lipids is critical for understanding the complicated lipid function in biological systems. But achieving both concurrently is challenging.

Like all living beings, human physiological processes are influenced by circadian rhythms. The disruption of our internal clocks due to an increasingly unbalanced lifestyle is directly linked to the ...