Tumor metastasis is a multi-step cascade process driven by molecular factors such as genetic mutations, epigenetic changes, and post-translational modifications. The tumor microenvironment (TME) plays ...

Cells have a mailing system of sorts. They can release tiny molecular balls, called extracellular vesicles (EVs), that contain biological matter or messages and attach to other cells to share whatever ...

As the second leading cause of death globally, cancer is a worldwide health crisis, particularly as life expectancies continue to increase. In its final stages, cancer spreads throughout the body in a ...

Researchers have developed an in vitro cancer model to investigate why breast cancer spreads to bone. Their findings hold promise for advancing the development of preclinical tools to predict breast ...

Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental factors and lifestyle, such as poor diet, sedentarism, obesity, smoking or ...

Researchers have identified a stress-activated control mechanism that helps breast cancer cells reshape gene activity to ...

Frontiers in Cell and Developmental Biology is delighted to present the ‘Reviews and Advances’ series of article ...

Researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer. LMU researchers have discovered how the interplay ...

Breast cancer is able to modify the lymphatic vessels through which it travels to the draining lymph nodes. From there, it ...

Extracellular vesicles are tiny spheres that cells release to send molecules or messages to other cells, often as a means of seeding cancer elsewhere in the body. In a new study, researchers found ...