Among the diverse methods for protein analysis, N-terminal sequencing stands out as a powerful tool for determining the amino acid sequence of proteins and peptides. This article delves into the ...

Here we describe the 1.8 Å resolution crystal structure of the N-terminal, heparin-binding domain of APP (residues 28–123), which is responsible, among other things, for stimulation of neurite ...

The fragments also directly compromise synapses they encounter along the way, according to a preprint posted February 24 on bioRxiv. Specifically, tau fragments containing the microtubule binding ...