Receptor protein tyrosine phosphatases are cell membrane-localized proteins. They are regulators of cell–cell contacts and are also considered likely to be tumor suppressors but how they function is ...

Scientists have unlocked new details on important receptor proteins—promising targets for the creation of novel drugs for metabolic conditions ranging from diabetes to obesity and inflammatory ...

Lefkowitz started to trace cell receptors in 1968. Using radioactivity, he managed to unveil several receptors, including one for adrenalin, the β-adrenergic receptor. His team then extracted the ...

Taste, pain, or response to stress — nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University of ...

If a prostate cancer cell were a car, the androgen receptor (AR) would be part of its ignition system, enabling cancer cells to respond to hormonal signals that drive growth. For decades, therapies ...

Despite being one of our key senses, the molecular mechanisms of smell remain poorly understood. Mason Wakely sniffs out the ...

Scientists from the Riken Center for Sustainable Resource Science (CSRS) in Japan have identified an ancient protein that, with modifications, could confer broad-spectrum protection for plants against ...