Researchers have confirmed that neuropeptide somatostatin can improve cognitive function in the brain. A research group of Professor Seung-Hee Lee from the Department of Biological Sciences at KAIST ...

Objective: Somatostatin (SST) is secreted by islet δ-cells and by extraislet neuroendocrine cells. SST receptors have been identified on α- and β-cells, and exogenous SST inhibits insulin and glucagon ...

Optimal biochemical control cannot be attained by long-acting somatostatin analog monotherapy in a large proportion of patients with acromegaly. Such therapy might result in increased mortality, poor ...

Different types of interneurons are important in shaping cortical information processing; however, the mechanisms by which they regulate sensory coding is unclear. Inhibition is typically proposed to ...

Inhibiting the hormone somatostatin may be a new treatment strategy to prevent dangerous blood glucose drops in type 1 diabetes. This has been shown by a study conducted at, among others, the ...

Somatostatin analogues are medicines that stop your body from making too many hormones. Some neuroendocrine tumours (NETs) make large amounts of hormones. This can cause symptoms. Somatostatin ...

Chemokine Receptor CXCR4 Expression in Colorectal Cancer Patients Increases the Risk for Recurrence and for Poor Survival One patient developed renal insufficiency, and another patient developed ...

A phase I trial of a novel mTOR inhibitor AP23573 administered weekly (wkly) in patients (pts) with refractory or advanced malignancies: A pharmacokinetic (PK) and pharmacodynamic (PD) analysis No ...

What am I looking at? This image shows a 1-millimeter-thick coronal slice (from top to bottom) through the brain of a mouse, with neurons that produce somatostatin in purple (1) and pyramidal neurons ...

This may look like an abstract work of art, with bold splashes of purple paint. In fact, the purple areas in this image are cells that make the neurotransmitter somatostatin, which is produced all ...