Nitrogen signal transduction plays a pivotal role in maintaining cellular metabolic balance by integrating environmental cues and internal nutrient levels. At the heart of this coordination are PII ...
Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...
Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2
In recent years, immune checkpoint therapy headed by programmed death receptor 1 (PD-1) and programmed death receptor-ligand 1 (PD-L1) has been proven to be safe and effective. However, clinical ...
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