The scientist who discovered hybridization and the "other" double helix describes what it meant to biology. By Alexander Rich Fifty-two years ago I was venturing to the basement of Cal Tech chemistry ...

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...

Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...

Thomas Gingeras did not intend to upend basic ideas about how the human body works. In 2012 the geneticist, now at Cold Spring Harbor Laboratory in New York State, was one of a few hundred colleagues ...

Significant advancements in gene silencing and gene editing offer new hope for treating rare disorders. Techniques like RNA ...

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet ...

“Our findings show that RNA-based testing can uncover hidden risks in multiple myeloma that DNA tests alone miss,” study ...

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell's protein-making machinery. rRNA accounts for much of the RNA in a cell, and it's crucial for life.