The Purdue University Institutional Biosafety Committee (IBC) reviews research protocols involving the use of recombinant DNA (rDNA), synthetic nucleic acids, and/or biohazardous agents that present a ...
The programmed polar RFBs that establish unidirectional replication have been proposed to initiate recombination within the rDNA at a constant rate during each S phase. Normally, these HR events ...
Eliminating either Pch2p or Sir2p also results in increased meiotic recombination in the rDNA. In the absence of Pch2p and Sir2p, the nucleolus becomes occupied by the meiotic recombination ...
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