BMJ10d
Global, regional and national burden of rheumatoid arthritis 1990–2017: a systematic analysis of the Global Burden of Disease study 2017
Objectives To provide the level and trends of prevalence, incidence and disability adjusted life years (DALYs) for rheumatoid arthritis (RA) in 195 countries from 1990 to 2017 by age, sex, ...
BMJ7d
Cell and transcriptomic diversity of infrapatellar fat pad during knee osteoarthritis
Objectives In this study, we employ a multiomic approach to identify major cell types and subsets, and their transcriptomic profiles within the infrapatellar fat pad (IFP), and to determine ...
BMJ2d
Elevated EPSTI1 promote B cell hyperactivation through NF-κB signalling in patients with primary Sjögren’s syndrome
2 Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, China Correspondence to Hua Chen, Department of Rheumatology and Clinical Immunology, Peking Union Medical ...
BMJ11d
Diagnosis of osteoporosis in statin-treated patients is dose-dependent
Objective Whether HMG-CoA-reductase inhibition, the main mechanism of statins, plays a role in the pathogenesis of osteoporosis, is not entirely known so far. Consequently, this study was set out to ...
BMJ2d
POS0095 CaMK4 CONTROLS T REGULATORY CELL METABOLISM AND DEFINES THEIR FUNCTION AND STABILITY IN SYSTEMIC LUPUS ERYTHEMATOSUS
Background Calcium/Calmodulin-dependent protein kinase IV (CaMK4) is a serine kinase expressed in CD4 T cells whom activity is increased in patients with active systemic lupus erythematosus (SLE). We ...
BMJ6d
Risk of venous thromboembolism in knee, hip and hand osteoarthritis: a general population-based cohort study
4 Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University, Changsha, China 5 National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, ...
BMJ10d
Contrasting contributions of TNF from distinct cellular sources in arthritis
2 Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology RAS, Moscow, Russian Federation Objectives Neutralisation of tumour necrosis ...
BMJ2d
AB1138 High levels of anti-u1rnp and anti-sm in mixed connective tissue disease patients
Background The mixed connective tissue disease (MCTD) is an autoimmune systemic disease characterised by clinical manifestations that are included in systemic lupus erythematous (SLE), scleroderma ...
BMJ11d
Single-cell RNA-seq analysis reveals the progression of human osteoarthritis
2 Biomedical Institute for Pioneering Investigation via Convergence and Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing, China 3 Beijing Advanced Innovation ...
BMJ11d
Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression
1 University of Leeds Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, UK Background The human enthesis conventional T cells are poorly characterised. Objectives To study the biology ...
BMJ2d
AB0021 REAL LIFE DATA ON TAPERING AND DISCONTINUATION OF ANAKINRA TREATMENT IN RECURRENT PERICARDITIS: AN INTERNATIONAL REGISTRY
2 University of Torino, Department of Medical Sciences, Città Della Salute E Della Scienza Di Torino Hospital, Torino, Italy 3 Department of Medical Sciences, Surgery and Neurosciences, Research ...
BMJ3d
Free radicals and inflammation
Free radicals and inflammation. P G Winyard, D R Blake, C H Evans. (Pp 272; DM238.) Basle: Birkhauser Verlag AG, 2000. ISBN 3-7643-5851-3. Understanding the genesis, propagation, and persistence of ...