San Francisco 49ers running back Christian McCaffrey is a strong favorite for the Comeback Player of the Year award.

If the 49ers win Sunday in Houston, they’ll match their overall win total from last season and they’ll be alone atop the NFC ...

San Francisco's Christian McCaffrey and George Kittle pose challenges for Houston's defense, and 49ers' pass rush will be key ...

San Francisco 49ers' team reporter Briana Jeannel named Head Coach Kyle Shanahan the heart and soul of the team. She also ...

Christian McCaffrey’s record-breaking run faces its toughest test yet as the San Francisco 49ers running back battles the Houston Texans’ top-ranked defense.

The NFL is far more reactive than it is proactive. Which makes Friday's reminder memo about the gambling policy, one day ...

Mac Jones has been a massive addition to the San Francisco 49ers this offseason. The team is 4-1 when he starts this season, ...

The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

A week after the San Francisco 49ers improbably dominated the NFL's second-ranked offense, they'll be given a far less ...

San Francisco 49ers head coach Kyle Shanahan detailed the team's latest injury report, opened up about his pregame speeches, ...

Pearsall's absence should lead to another start for Kendrick Bourne, who has been riding a hot streak in 2025. Bourne, who ...

Take a look at the injury report for the San Francisco 49ers (5-2), which has 16 players listed (including Christian ...