Many trials that measure the efficacy and safety of antidepressants for MDD exclude one third of real-world patients with the ...

A meta-analysis of randomized trials suggests fecal microbiota transplantation can ease depressive symptoms, with stronger effects reported for endoscopic or enema delivery, according to researchers ...

General anesthesia leads to better functional outcomes than conscious sedation in stroke patients with large vessel occlusion ...

Trials should assess overall survival to evaluate potential harm, with crossover limited to avoid confounding treatment ...

A new study suggests that low-dose radiation therapy could fill the treatment gap between pain medications and joint ...

Polypills for HFrEF are being tested in RCTs, and if they’re approved, experts want to be ready for their rollout and use.

When it comes to trials of any drug, size matters, potentially giving the World Health Organization's (WHO) gloomy verdict on Gilead Sciences' COVID-19 treatment remdesivir an edge over the company's ...

The phase 3 DREAM3R study randomized patients 2:1 to receive durvalumab 1500 mg every 3 weeks plus chemotherapy every 3 weeks for 4 to 6 cycles, followed by durvalumab maintenance 1500 mg every 4 ...

Millions of adults all over the world endure chronic constipation — an awkward situation marked by hard, painful, or ...

Pediatric progressive myopia is a growing global public health concern, linked to serious ocular complications including ...

Sepsis remains one of the leading causes of mortality in hospitalized patients worldwide, and innovative therapeutic ...

Eli Lilly’s oral GLP-1 therapy, orforglipron, met all primary and key secondary endpoints in the Phase III ACHIEVE-2 and ACHIEVE-5 studies, showing significant A1C reduction, weight loss, and ...