Why do some brain cells die first in HD? New study shows changes in gene activity begin at birth in mice, especially in striatum & cortex—mapped with spatial & single-cell tools. A new study in mouse ...

Not every news source put out a headline that exaggerated the results. Some of the more level-headed articles underscored that the results “show promise”, were “a cause for hope”, were “preliminary ...

As we begin 2025, we look back on all of the Huntington’s disease research news and progress the field has made in the last 12 months. May 7 is Brain Donation Awareness Day. Today we highlight the ...

SKY-0515, an oral drug, safely lowers huntingtin in people with HD and may also reduce PMS1. This could offer a possible two-pronged approach to treat HD. SKY-0515 is now being tested in a larger ...

Figuring out how many people have 36 or more CAG repeats, but never show up to a doctor, is a bit like an iceberg. There’s a ...