The association of bicuspid aortic valve with aortic stenosis, aortic regurgitation, and infective endocarditis has been known for almost 150 years and with dissection of the aorta for 75 years. 1 ...

Background Coarctation of the aorta (CoA) has good modern results, but large multicentre longitudinal data on outcomes, especially hospital resource utilisation through childhood and adolescence, are ...

Background A pathway incorporating an option for early discharge based on a single low level of high-sensitivity cardiac troponin I (hs-cTnI) at presentation increases the proportion of patients ...

Diabetes mellitus is highly prevalent in patients with coronary atherosclerosis. As a result of several factors, including a ...

Background Baseline health and driving data might allow clinicians to personalise medical driving restrictions after implantable cardioverter-defibrillator (ICD) implantation. Methods Using 22 years ...

Milestone articles have highlighted the frequency and types of statistical errors in research,1–5 yet fundamental errors ...

A recent meta-analysis has shown that loneliness and social isolation are risk factors for coronary heart disease and stroke.1 These latest findings, specific to cardiovascular outcomes, are ...

Legalisation of medical and recreational cannabis commerce is spreading around the world, associated with increased use1 and falling perception of the risk.2 Frequent cannabis use has increased in ...

The 2024 European Society of Cardiology (ESC) Guidelines on elevated blood pressure (BP) and hypertension reflect a shift from binary thresholds towards a risk-based management approach that aims to ...

Functional mitral regurgitation (FMR) remains a significant challenge in the management of heart failure (HF), characterised by poor prognosis and high morbidity.1 As the predominant valvular ...

Objective To investigate the prognostic impact of left ventricular (LV) diastolic dysfunction in patients with moderate aortic stenosis (AS) and preserved LV systolic function. Methods Patients with a ...

Objectives This updated hierarchical Bayesian meta-analysis aims to integrate the latest randomised controlled trials (RCTs) on the use of cerebral embolic protection (CEP) in transcatheter aortic ...