Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

The 49ers could open wide receiver Brandon Aiyuk's 21-day practice window as soon as next week, coach Kyle Shanahan said ...

As the Tampa Bay Buccaneers prepare for another heated NFC South battle with the New Orleans Saints, the defense once again ...

The San Francisco 49ers got extremely lucky finding Eddy Pineiro after the year started. He's been even better than Kyle ...

The Houston Texans are getting ready for their Week 8 matchup against the San Francisco 49ers, but they will be without two key wide receivers for the game. Acc ...

The 49ers' top quarterback has missed five of seven games this season so far. Here's the latest on his status for Week 8.

Along with Purdy, the 49ers have also ruled out wide receiver Ricky Pearsall for his fourth-straight game with a knee injury, leaving this San Francisco 49ers offense a bit depleted in multiple ...

While the San Francisco 49ers have gained an early edge with victories against fellow 5-2 rivals Los Angeles and Seattle, right tackle Colton McKivitz knows a Week 8 visit to Houston offers a unique ...

The Jaguars cannot continue to attempt north of 40 passes per game when receivers aren’t reeling in passes. That’s not to say Lawrence is absolved from overthrows or misses, but even when he’s putting ...

The only player in Baltimore with an injury designation heading into the weekend is quarterback Lamar Jackson.

WWE superstar The Miz comments on getting older as a wrestler and the differences between what his body feels like now as ...