Scientists have achieved the first real-time visualization of how 'excited-state aromaticity' emerges within just hundreds of femtoseconds and then triggers a molecule to change from bent to planar ...
Imagine a microscopic locomotive moving back and forth along a track, propelling itself without any external force. At the molecular level, this concept forms the foundation of molecular motors -- ...
Researchers at Washington University in St. Louis have developed a method to peer into biomolecular condensates, which could lead to a better understanding of condensate functions and their impairment ...
Each cell in your body relies on precise communication with other cells to function properly. At the center of this process ...
Intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their ...
Similarly, basis set convergence is more consistent for relaxed geometries, as the electron distribution and correlation effects are more accurately aligned with the optimized structure ...
Laboratory of Computer-Aided Molecular Design, Division of Medicinal Chemistry, Otto-Loewi Research Center, Medical University of Graz, Neue Stiftingtalstr. 6/III, A-8010 Graz, Austria ...
The authors’ structure unambiguously places UM171 in the company of a limited number of other molecular glue degraders, including anticancer compounds called aryl sulfonamides and ...
so having the cryo-EM structure was very helpful," Yeo said. "It was stunning to see the direct overlay of the small molecule and these cancer mutations, which we could not have imagined without ...
According to Gates, Jobs once suggested that he should have experimented with LSD (lysergic acid diethylamide) to enhance his creativity and design better products. Notably, Jobs, known for his ...
Mescaline, a natural hallucinogen known since ancient times, was not only a favorite of artists and bohemians but also a mainstay of brain research throughout the first half of the 20th century, until ...