Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes ...

Gear-obsessed editors choose every product we review. We may earn commission if you buy from a link. Why Trust Us? A study out of Japan showed how targeting genes can regrow teeth in animals. Now ...

Research Associate of the American Cancer Society. Present address: Department of Pharmacology, University of Florida, Gainesville, Florida. Postdoctoral Trainee in Pharmacology, on leave from the ...

It was expected that by analysing the characteristics of chromosome and nucleolus behaviour, abnormalities specific to the internal organization of tumour cells might be detected. The present ...

Long non-coding RNAs (lncRNA) are a type of non-coding RNAs (ncRNAs) that exceed 200 nucleotides in length. lncRNAs are a relatively abundant component of the mammalian transcriptome and have been ...

Alongside organelles such as mitochondria and Golgi apparatuses, membraneless structures help compartmentalize the cytoplasm, as well as the interior of the nucleus. In contrast to organelles with a ...