Both the Philadelphia 76ers and Boston Celtics may be without some key players during Wednesday night's matchup, including two stars.

Boston Celtics forward Jaylen Brown acknowledged their mistakes after losing to the Philadelphia 76ers on Wednesday.

Although initially questionable due to hamstring tightness, Boston Celtics star Jaylen Brown will play against the Philadelphia 76ers.

The Boston Celtics will tip off their 2025-26 campaign on Wednesday as they get set to take on the Philadelphia 76ers. More news: Celtics' Anfernee Simons Know

Celtics guard Derrick White revealed that the ball didn't reach who it was supposed to at the end of Boston's season-opening loss.

The new NBA season begins with the Philadelphia 76ers taking on the Boston Celtics at TD Garden. After a rough 24-58 season and a 1-3 preseason, the Sixers hope Joel Embiid’s return from knee surgery can spark a turnaround.

The 2025-26 NBA season kicks off with a thrilling matchup between the Boston Celtics and Philadelphia 76ers on October 22, 2025. Hosted at TD Garden,

Wednesday night marks the beginning of a fresh start for the Philadelphia 76ers, and they surely need it. Last year, the Sixers turned in their worst season of

The Celtics' 2025-26 season tips off tonight with a matchup against a bitter rival. Get our best player prop bets for 76ers vs. Celtics, plus a Jaylen Brown player prop parlay.

The Celtics showed promising growth, but also a lot of areas where Boston needs to get better as a team and on a more granular level.

Joel Embiid struggled to find his rhythm in the Philadelphia 76ers' season-opening 117–116 win over the Boston Celtics, shooting just 1-of-9 from the field for four points.

Philadelphia 76ers star Joel Embiid addresses his tough night in his return against the Boston Celtics on Wednesday.