Stock futures are pointing to a slightly lower open for major indexes on Wednesday as investors respond to a slew of earnings reports from retailers and brace for a big speech later in the week by Federal Reserve Chair Jerome Powell.

Dow Jones futures edge lower amid mounting concerns over stretched valuations and the sustainability of the AI-driven rally. Market sentiment remains cautious as the FOMC Meeting Minutes indicated that most Fed members favored holding rates steady.

Stock index futures were muted on Thursday, a day after Wall Street ended mostly lower as investors continued to await Federal Reserve Chair Jerome Powell's speech at Jackson Hole on Friday.

S&P 500 futures are down 0.1%. Dow Jones Industrial Average futures are dipping 0.1%. Nasdaq 100 futures are slipping 0.1%. On Monday, the Dow Jones Industrial Average fell 34 points, or 0.08%, to 44,

Futures tracking Canada's main stock index were flat on Wednesday, as investors await the U.S. Federal Reserve's annual symposium later this week for clues on the monetary policy path.

Crude futures settled higher amid a lull in Russia-Ukraine news, with gains supported by a bigger-than-expected weekly decline in U.S. crude oil stocks.

S&P 500 futures are down 0.3%. Dow Jones Industrial Average futures are dipping 0.3%. Nasdaq 100 futures are slipping 0.4%. On Tuesday, the Dow Jones Industrial Average rose 10 points, or 0.02%, to 44922,

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