The 3 patients who underwent surgical gallstone removal all ultimately recovered well, including one who developed acute chest syndrome. As cholelithiasis and choledocholithiasis are common in ...

The targeting of factor XII activation is a key strategy in offering long-term prophylaxis to patients with hereditary angioedema. Garadacimab, a therapeutic targeting factor XII activation, has been ...

Recent research has shown that intestinal barrier disruption worsens experimental AIP by facilitating the translocation of pathogenic bacteria, including Staphylococcus sciuri, from the gut to the ...

Pretreating human astrocytes with interleukin (IL)-17A, IL-10, and IL-6 could help differentiate between serum obtained from anti-aquaporin 4 (AQP4) antibody-positive NMOSD and healthy controls.

Patients with GPP had high treatment persistence on ixekizumab, with significant PASI score improvements. Ixekizumab maintained a favorable safety and efficacy profile across psoriasis subtypes, ...

Hemophagocytic lymphohistiocytosis, a severe hyperinflammatory condition, can complicate FNAIT, making early diagnosis critical. Hemophagocytic lymphohistiocytosis (HLH), a life-threatening ...

A phase 3 study is ongoing to confirm the survival benefit of venetoclax plus azacitidine in patients with treatment-naive high-risk MDS. The combination of venetoclax plus azacitidine was well ...

Collaboration between clinicians and caregivers is a key component to supporting effective use of the CGI-I Non-seizure Symptoms measure. The CGI-I Nonseizure Symptoms measure was developed to be ...

This is the first reported case of a child with PWS who was further diagnosed with LGS. “To our knowledge, this is the first reported case of LGS in a pediatric patient with Prader-Willi syndrome in ...

Having RA and type 1 diabetes increased the risk of developing PAH, and a link was found between a genetic risk of PAH and an increased risk of PAH. Bidirectional Mendelian randomization (MR) analysis ...

The use of short femoral stems may offer a suitable surgical strategy for addressing the complex femoral anatomy associated with achondroplasia. Total hip arthroplasty (THA) in individuals with ...

The present study did not find genetic evidence of a causal association between PBC and pregnancy outcomes, which is consistent with the findings of several previous studies. Genetically predicted ...