Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a ...

While the San Francisco 49ers have gained an early edge with victories against fellow 5-2 rivals Los Angeles and Seattle, right tackle Colton McKivitz knows a Week 8 visit to Houston offers a unique ...

C.J. Stroud and the Houston Texans must overcome yet another obstacle as they take on the San Francisco 49ers in Week 8.

Quarterback Brock Purdy will miss his fourth straight game and sixth in the past seven weeks for the San Francisco 49ers with ...

The San Francisco 49ers enter Week 8 facing renewed questions about the health of their starting quarterback, Brock Purdy.

The San Francisco 49ers have a better record than the Houston Texans, but the oddsmakers have the Texans as favorites. They ...

NFL Media Insider Mike Garafolo reports Philadelphia Eagles wide receiver A.J. Brown is out with a hamstring injury vs. the ...

For Texans edge rusher Will Anderson Jr., he's motivated to keep the wheels turning to make that turnaround happen. But ...

NFL Reporter Jane Slater breaks down the San Francisco 49ers' success with quarterback Mac Jones under center this season and previews their upcoming matchup against the Houston Texans on Sunday.

San Francisco 49ers head coach Kyle Shanahan detailed the team's latest injury report, opened up about his pregame speeches, ...

The Houston Texans receive unfortunate injury updates for the San Francisco 49ers game regarding Nico Collins and Christian ...

The Houston Texans (2-4) are listed as close favorites (-2) against the San Francisco 49ers (5-2) on Sunday, October 26, 2025. The game's total has been listed at 42 points. Are you looking to make a ...