Chlorpromazine Dose & Frequency • 25–50 mg orally every 6–8 hours • If severe: IM/IV can be used in the same dosing range Duration • Persistent hiccups: usually 1–3 days • Intractable hiccups: 3–7 days, occasionally up to 10–14 days • Stop once hiccups resolve (not for chronic use due to side effects) Effectiveness • 60–80% response rate in most clinical studies Metoclopramide Dose & Frequency • 10 mg every 6–8 hours (oral or IV) Duration • Typically 2–5 days • Stop if hiccups improve • Avoid lo
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