Not All Anemia is Iron Deficiency! A female patient presents with fatigue and Hb of 8.5. You start Iron supplements. 2 months later? No improvement. 📉 The Missed Clue: The MCV (Mean Corpuscular Volume). If MCV is > 100 fL, it's Macrocytic Anemia, not Microcytic (Iron deficiency). Common Causes of Macrocytosis: Vitamin B12 / Folate Deficiency Liver Disease Alcoholism Drugs (Methotrexate, Phenytoin) HYPOTHYROIDISM (The silent culprit!) 🦋 💡 Clinical Pearl: If you see Anemia associated with: ✅ Ob
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📌 Macrocytic Anemia – Quick Guide ✅ Definition: MCV > 100 fL ✅ Types: Megaloblastic 🧬 – Defective DNA synthesis Non-megaloblastic 🔄 – Normal DNA synthesis 🔬 Megaloblastic Anemia ⚡ Causes: Vitamin B12 Deficiency 🧠 (Neurological symptoms present) Folic Acid Deficiency 🌱 (No neurological symptoms) ⚡ Peripheral Smear: Hypersegmented neutrophils 🔍 Macro-ovalocytes 🩸 | Entice
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