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🔦 Shining a light on “dark kinases” 🔦 WEHI and Monash Institute of Pharmaceutical Sciences (Monash University) researchers have uncovered new details about the understudied “dark” kinase PSKH1. Excitingly we’ve found PSKH1 can have its activity tuned up or down depending on which proteins it interacts with in cells and the level of calcium. In some cancers and kidney diseases PSKH1 is dysregulated, meaning knowledge of how it works could open doors for novel treatments. Some kinases are consid
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🔦 Shining a light on “dark kinases” 🔦 WEHI and Monash Institute of Pharmaceutical Sciences (Monash University) researchers have uncovered new details about the understudied “dark” kinase PSKH1. Excitingly we’ve found PSKH1 can have its activity tuned up or down depending on which proteins it interacts with in cells and the level of calcium. In some cancers and kidney diseases PSKH1 is dysregulated, meaning knowledge of how it works could open doors for novel treatments. Some kinases are consid
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Biology on Instagram: "Way to happiness. Kinesin motor proteins transport dopamine-filled vesicles from the neuron's cell body, where they are synthesized, along microtubule tracks to the axon terminal, or synapse. This process, known as anterograde transport, is essential for ensuring a constant supply of dopamine for neurotransmission. 📹 by MGlomb3d&interactive (yt) #neuroanatomy #neurotransmitters #bioscience #biology #neurobiology"
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