My patient has been on Trizepatide for 3 years, and we’ve talked a lot about its role in Lipedema. While many patients may lose significant weight, and she herself has lost 140 pounds, those with Lipedema often notice less fat loss from the calves, ankles, arms, and affected areas, and more from visceral fat. An interesting benefit of GLP-1 agonists is their effect on improving inflammation, which can be helpful even before surgery. However many patients can reach a point of being “maxed out,” r
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